
Tracking DLB Symptoms Before Diagnosis: Are Men and Women Different?
Dr. Tanis Ferman, a NAPS Clinical Core investigator, co-authored a study exploring how dementia with Lewy bodies (DLB) symptoms differ between men and women in the two years before diagnosis.

Unlocking Brain Health: New Study Explores Breakthrough MRI Technique for Early Parkinson’s Detection
New research from France highlights a promising brain scan technique – neuromelanin-sensitive MRI – that measures dopamine in a key brain region affected by Parkinson’s disease (PD).

New Global Consensus on RBD Treatment: What You Need to Know
Explore the latest consensus on managing RBD, led by NAPS Investigator Dr. Aleksandar Videnovic and the International RBD study group.

2025 International RBD Study Group Meeting
NAPS Consortium members took center stage, presenting on key topics and leading discussions on neurophysiology, RBD ethics, longitudinal data, and patient risk communication, just to name a few.

Elevated α-Synuclein Aggregate Levels in the Urine of Patients with Isolated REM Sleep Behavior Disorder and Parkinson's Disease
New research is shedding light on a potential breakthrough for diagnosing Parkinson's disease (PD). A study using surface-based fluorescence intensity distribution analysis (sFIDA) found that α-synuclein aggregates, commonly associated with PD, can be detected in urine samples.

New Alzheimer's Test Approved by FDA—What to Know
The FDA has approved the first blood test to assist in diagnosing Alzheimer's.

Ultraprocessed Foods Linked to Early Symptoms of Parkinson’s
A recent study of over 42K participants published in Neurology reveals that a diet high in ultraprocessed foods may increase the likelihood of developing early signs of Parkinson’s disease, including probable RBD. Participants who ate the most ultraprocessed foods were 2.5 times more likely to show early symptoms like constipation, reduced smell, and sleep disturbances. While the findings aren’t conclusive, they underscore the importance of diet in brain health.

REM Sleep Behavior Disorder: How Do We Decide if REM EMG Activity is Excessive?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts.
The diagnosis of REM sleep behavior disorder needs, in addition to dream enactment behavior, a determination that EMG activity is excessive during REM sleep. But what is excessive? In this podcast, the team discusses how a practicing polysomnographer can make this determination.

REM Sleep Behavior Disorder: Discussing the Diagnosis and the Ethics of Disclosure
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. In this podcast, the team explores ethics and empathy.

REM Sleep Behavior Disorder (RBD): Personal Perspectives and Research Priorities
Dr. Carlos Schenck, who, alongside Mark Mahowald, was the first to describe RBD, continues to play an active role in the field, currently serving on the NAPS Scientific Advisory Board. In a recent publication in the Journal of Sleep Research, he reviewed key milestones in RBD and synucleinopathy research and discussed the current research priorities.

RBD Question of the Week❓💤💡 How is RBD managed?
This week, we have NAPS Investigator, Dr. Aleksandar Videnovic at Harvard University and Massachusetts General Hospital to answer one of our most pressing RBD questions.

RBD Question of the Week❓💤💡 How is RBD diagnosed?
This week, we have NAPS Investigator, Dr. Aleksandar Videnovic at Harvard University and Massachusetts General Hospital to answer one of our most pressing RBD questions.

REM Sleep Behavior Disorder: What factors affect risk of progression to Parkinson pathology?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.

REM Sleep Behavior Disorder: How near are we to preventing Parkinson’s Disease?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.

REM Sleep Behavior Disorder: Can we test for Parkinson pathology?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.

REM Sleep Behavior Disorder: How does Parkinson pathology evolve?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.

Longitudinal Network Changes and Phenoconversion Risk in Isolated REM Sleep Behavior Disorder
🧠 Exciting news in neuroscience! 🧠
Dr. Ron Postuma and colleagues have co-authored a groundbreaking study in Nature Communications.

Annual International Lewy Body Disease Congress
The annual International Lewy Body Disease Congress meeting took place in Amsterdam in January 2025.

Neurogenic Orthostatic Hypotension is Common in Isolated REM Sleep Behavior Disorder
Dr. Elizabeth Coon talks with Dr. Mitchell G. Miglis about the frequency of orthostatic hypotension in isolated REM Sleep Behavior Disorder.

Longitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum
Exciting new research led by Dr. Kejal Kantarci, co-leader of the NAPS Neuroimaging Core, at Mayo Clinic.
Her study on FDG-PET brain imaging has uncovered crucial insights into brain metabolism changes during mild cognitive impairment.