REM Sleep Behavior Disorder (RBD): Personal Perspectives and Research Priorities
Dr. Carlos Schenck, who, alongside Mark Mahowald, was the first to describe RBD, continues to play an active role in the field, currently serving on the NAPS Scientific Advisory Board. In a recent publication in the Journal of Sleep Research, he reviewed key milestones in RBD and synucleinopathy research and discussed the current research priorities.
RBD Question of the Week❓💤💡 How is RBD managed?
This week, we have NAPS Investigator, Dr. Aleksandar Videnovic at Harvard University and Massachusetts General Hospital to answer one of our most pressing RBD questions.
RBD Question of the Week❓💤💡 How is RBD diagnosed?
This week, we have NAPS Investigator, Dr. Aleksandar Videnovic at Harvard University and Massachusetts General Hospital to answer one of our most pressing RBD questions.
REM Sleep Behavior Disorder: What factors affect risk of progression to Parkinson pathology?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.
REM Sleep Behavior Disorder: How near are we to preventing Parkinson’s Disease?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.
REM Sleep Behavior Disorder: Can we test for Parkinson pathology?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.
REM Sleep Behavior Disorder: How does Parkinson pathology evolve?
NAPS Co-Principal Investigator Dr. Brad Boeve teams up with Dr. Mike Silber, a member of the NAPS Scientific Advisory Board, for an episode on REM sleep behavior disorder (RBD) in the Mayo Clinic Sleep Medicine Podcasts. They explore the connection between RBD and synucleinopathies like Parkinson's disease.
Longitudinal Network Changes and Phenoconversion Risk in Isolated REM Sleep Behavior Disorder
🧠 Exciting news in neuroscience! 🧠
Dr. Ron Postuma and colleagues have co-authored a groundbreaking study in Nature Communications.
Annual International Lewy Body Disease Congress
The annual International Lewy Body Disease Congress meeting took place in Amsterdam in January 2025.
Neurogenic Orthostatic Hypotension is Common in Isolated REM Sleep Behavior Disorder
Dr. Elizabeth Coon talks with Dr. Mitchell G. Miglis about the frequency of orthostatic hypotension in isolated REM Sleep Behavior Disorder.
Longitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum
Exciting new research led by Dr. Kejal Kantarci, co-leader of the NAPS Neuroimaging Core, at Mayo Clinic.
Her study on FDG-PET brain imaging has uncovered crucial insights into brain metabolism changes during mild cognitive impairment.
Plasma pTau181 and Amyloid Markers Predict Conversion to Dementia in Idiopathic RBD
NAPS members from McGill University, led by NAPS Co-Principal Investigator, Ron Postuma, have published a groundbreaking study in Brain journal!
Dr. Wolfgang Singer Named Professor of Neurology: Advancing Autonomic Research at Mayo Clinic
NAPS Consortium Member Dr. Wolfgang Singer has been promoted to Professor of Neurology at the Mayo Clinic College of Medicine and Science.
IGLON5 Frequency in Idiopathic REM Sleep Behavior Disorder
Dr. Jeff Ratliff talks with Dr. Ron Postuma about the clinical features associated with IGLON5 positivity, emphasizing the implications for practitioners in diagnosing and treating sleep and movement disorders.
Post-Mortem Neuropathology of Idiopathic RBD: A Case Series
A recent publication from a large RBD cohort in Spain examined postmortem brain tissue from individuals who had RBD. This study showed there was abnormal synuclein in the cells that control atonia (muscle paralysis) during REM sleep in all the participants.
Validation of Automated Detection of REM Sleep without Atonia Using In-Laboratory and In-Home Recordings
A recent study led by NAPS investigators Drs. Erik St. Louis and Brad Boeve from Mayo Clinic validated the use of an in-home sleep recording device to detect REM sleep without atonia.
The RBD Severity Scale
The RBD Severity Scale, also known as the "IRBD-SSS" (International REM Sleep Behavior Disorder Study Group Symptom Severity Scale), is a tool used to assess the severity of REM Sleep Behavior Disorder (RBD) symptoms by evaluating the frequency and intensity of dream content, vocalizations, body movements, and potential injuries experienced by the patient, often with input from their bed partner as well.New research sheds light on REM sleep behavior disorder and its link to neurodegenerative diseases like Parkinson's. 🧠🔬💤
A Pontine-Medullary Loop Crucial for REM Sleep and its Deficit in Parkinson’s Disease
New research sheds light on REM sleep behavior disorder and its link to neurodegenerative diseases like Parkinson's. 🧠🔬💤
Does Your Body Composition Affect Your Risk of Dementia or Parkinson's?
Researchers found that higher levels of belly and arm fat are associated with increased risk of developing Alzheimer's and Parkinson's diseases, especially among those with lower muscle strength. The study showed that individuals with high belly fat had a 13% higher risk, and those with high arm fat had an 18% higher risk of these neurodegenerative diseases compared to their counterparts with lower fat levels.
RBD Question of the Week❓💤💡 How confident are you in predicting phenoconversion/transformation of neurodegenerative conditions in people with RBD?
This week, we have Drs. Roneil Malkani from Northwestern University and Ron Postuma from McGill University to answer one of our most pressing RBD questions.