NAPS Data
NAPS began collecting longitudinal, comprehensive clinical data and biomarkers in 2018, at 10 sites, on a large cohort of participants with polysomnogram-confirmed idiopathic RBD. Baseline characteristics and overview are available in this publication.
Information about the NAPS RBD cohort will be updated periodically.
NAPS is dedicated to providing data and biological samples to qualified researchers. Submit your request for data/samples and review our data sharing policy by clicking the links below.
This repository is under review for potential modification in compliance with Administration directives.
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Data Request
The form is designed to facilitate the sharing of data and biospecimens among researchers while ensuring compliance with ethical standards and regulations. It also helps streamline the approval process, fostering collaborative research and promoting transparency in the scientific community.
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Data Access Policy
The goals of the project can be best achieved through collaborative and open access to data and biospecimens, while respecting the intellectual contributions of principal- and co-investigators. This document presents the policy for access to data, access to biospecimens, and publications.
Forms for NAPS Sites
Available to NAPS personnel only.
NAPS Participants and Clinical Visits, as of 1/31/2025
| RBD | Control | |
|---|---|---|
| 1 | 525 | 21 |
| 2 | 273 | 1 |
| 3 | 224 | N/A |
| 4 | 118 | N/A |
| 5 | 47 | N/A |
| 6 | 7 | N/A |
| Total | 1294 | 22 |
| Total NAPS1 | NAPS1 to NAPS2 Rollover | New NAPS2 | Total NAPS2 | |
|---|---|---|---|---|
| Number of Unique Participants | 381 | 228 | 165 (21 controls) | 393 (21 controls) |
| Blood | CSF | |
|---|---|---|
| 1 | 514 | 91 |
| 2 | 333 | 71 |
| 3 | 199 | 40 |
| 4 | 114 | 21 |
| 5 | 45 | 11 |
| 6 | 7 | 1 |
| Total | 1212 | 235 |
NAPS Biofluid Samples, as of 1/31/2025
CSF = Cerebrospinal fluid
Blood in most cases includes plasma, buffy, DNA, serum, RNA PaxGene
NAPS Neuroimaging and Polysomnograms, as of 1/31/25
| Procedure | Baseline | Follow-Up | Total |
|---|---|---|---|
| MRI | 230 | 9 | 239 |
| DaTscan | 222 | 0 | 222 |
| Polysomnogram | 385 | 63 | 224 |
Biomarker Collected
| Data Freeze Number | Contain Data Up To Listed Date | Data Freeze Completion Date |
|---|---|---|
| DF1 | 5/20/22 | 8/16/23 |
| DF2 | 1/31/24 | 10/21/24 |
| DF3 | 7/31/24 | 3/11/25 |
| DF4 | 1/31/25 | 6/17/25 |
| DF5 | 7/31/25 | In progress |
Data Freeze Dates
Data requests will be fulfilled using the most recent data freeze that is outside of the applicable embargo window. Data freeze completion date is used to determine embargo window. See Data and Specimen Policy for details.