RBD is characterized by the loss of normal muscle atonia during REM sleep, leading to the physical enactment of dreams. The spectrum of behaviors exhibited by individuals with RBD can vary widely, ranging from mild movements to more severe and potentially dangerous actions.

Safety is often overlooked when discussing REM Sleep Behavior Disorder (RBD), yet it remains crucial. Undiagnosed RBD poses risks beyond sleep disturbances, extending to potential harm to oneself or others. Here are specific suggestions to optimize safety in the setting of REM Sleep Behavior Disorder.

The epidermis holds clues to certain neurologic disorders. Learn about what specialists look for and how they interpret what they find.

Learn more about the work that we support from The Washington Post.

Aleksandar Videnovic, MD, Massachusetts General Hospital, Harvard Medical School, Boston, MA, talks on the establishment of the North American Prodromal Synucleinopathy (NAPS) Consortium.

As the name suggests, Frontotemporal dementia (FTD) affects the frontal lobe and/or temporal lobes of the brain. Signs and symptoms vary, depending on which part of the brain is atrophying, or shrinking. Genetic mutations and dysfunctional proteins in the brain have been linked to FTD.

In a paper published in The Lancet Neurology, a group of scientists, including NAPS Co-Investigator, Ronald Postuma, MD, MSc (McGill), argue that developing effective treatments for Parkinson’s disease demands a new way of classifying the disease for research purposes, one based not on clinical diagnosis but biology. The authors have called their biological model “SynNeurGe”.

Indu Subramanian (UCLA) speaks with REM Sleep Behavior Disorder (RBD) expert and NAPS Co-Investigator, Ronald Postuma, MD, MSc (McGill), about prodromal Parkinsons's disease and it's link to RBD.

Researchers uncover how brain fats are crucial for memory, identifying genes that could lead to treatments for Alzheimer's. This new understanding of fatty acids opens exciting avenues for neurodegenerative disease therapies.

“By focusing on RBD research, we have an unprecedented opportunity to develop clinical trials aimed at stopping the progression of neurodegenerative disorders, such as Parkinson’s, dementia with Lewy bodies, and multiple system atrophy. I can’t think of more rewarding work.”

– Aleksandar Videnovic, MD, MSc
Massachusetts General Hospital

Many studies have posed a-synuclein as a potential diagnostic and prognostic biomarker for Parkinson's Disease. Due to its abundance in the body, several modes for sample collection are currently being investigated, including tissue and fluid samples.

The professorship was created through a bequest from the late Reuben M. Morriss III and Barbara Burton Morriss to Washington University, to advance Alzheimer’s disease research.

Our team is committed to further the NAPS study's mission to support clinical care, advance discovery, promote education, and engage our community in order to improve the quality of life and care of individuals living with RBD. Learn more about the team at Emory University.

The 2nd Annual Center on Biological Rhythms and Sleep Symposium was held at the Washington University School of Medicine in St. Louis in May 2023.

Our team is committed to further the NAPS study's mission to support clinical care, advance discovery, promote education, and engage our community in order to improve the quality of life and care of individuals living with RBD. Learn more about the team at OHSU and VA Portland Health Care System (VAPORHCS).

Our team is committed to further the NAPS study's mission to support clinical care, advance discovery, promote education, and engage our community in order to improve the quality of life and care of individuals living with RBD. Learn more about the team at UCLA.

Our team is committed to further the NAPS study's mission to support clinical care, advance discovery, promote education, and engage our community in order to improve the quality of life and care of individuals living with RBD. Learn more about the team at The University of Minnesota.

Our team is committed to further the NAPS study's mission to support clinical care, advance discovery, promote education, and engage our community in order to improve the quality of life and care of individuals living with RBD. Learn more about the team at McGill University Health Centre Research Institute.

From Scientific American

Our team is committed to further the NAPS study's mission to support clinical care, advance discovery, promote education, and engage our community in order to improve the quality of life and care of individuals living with RBD. Learn more about the team at Washington University.